PURINE-REQUIRING AND PYRIMIDINE-REQUIRING MUTANTS OF SACCHAROMYCES CEREVISIAE
- 1 June 1952
- journal article
- research article
- Published by American Society for Microbiology in Journal of Bacteriology
- Vol. 63 (6) , 707-713
- https://doi.org/10.1128/jb.63.6.707-713.1952
Abstract
Genetic and nutritional analyses have been made of 7 purineless and 2 pyrimidineless mutants of S. cerevisiae. Allelism tests revealed 5 different genetic types in the purine- requiring group, 2 in the pyrimidine- requiring group. The purine auxotrophs could grow only on adenine or hypoxanthine and were competitively inhibited by guanine. Uracil, cytosine, 5-nitrouracil, uridine, and uridylic acid could be used by both pyrimidineless mutants.Keywords
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