Cross Transfusion as a Means of Determining Toxic Factors in Blood from Burned Animals

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Abstract
In expts. studying the effect of transfusion of blood from a burned animal (dog) to a normal animal, a method of cross transfusion was used which obtained blood from the vena cava (draining the burned area), and cross transfused large quantities (several hundred ml.) to and from the normal and burned animal. The avg. drop in blood pressure of dogs receiving blood from normal dogs was 19 mm. of Hg, compared to a drop of 42 mm. in dogs receiving blood from burned animals in the same quantity and same speed of injn. The mortality rate in 30 dogs receiving blood from the vena cava of normal animals was 16.6% compared to a rate of 27.7% in 18 dogs receiving blood from the vena cava of animals burned on the lower extremities and distal torso.

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