Chondrocalcinosis Articularis

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Abstract
Articular chondrocalcinosis has a familial incidence, affects both sexes and manifests itself clinically in the third decade of life. It is characterized by the development of arthritic episodes which occur at irregular intervals and are accompanied by general malaise and nonspecific serum protein changes. The multiple calcification of superficial layers of articular cartilage, has a slow but progressive course affecting the joints. The chondrocalcinosis may be defined as oligoarticular or polyarticular according to the number of joints affected. Generalized osteoarthritis eventually develops and progresses concurrently with a reduction in the X-ray signs of articular calcification and a lessening of the inflammation. The oligoarticular type with onset after the fifth decade usually remains stationary radiologically (clinically latent and mild). Attacks of rheumatic-fever, palindromic rheumatism, atypical rheumatoid arthritis, isolated calcification of the menisci and conditions associated with calcification of the fibrous cartilages should be taken into consideration in differential diagnosis. Therapy is symptomatic.

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