Inhibin in the Human Prostate

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Abstract
Inhibin-like protein, partially purified from the human prostate, was similar to that obtained from human seminal plasma under identical conditions. Concentration of inhibin in human prostate was 10-fold higher as compared to human testis and was active biologically and immunologically. The presence of a high amount of inhibin in prostate seems to be unique in humans. Inhibin concentration in benign prostatic hypertrophy tissue increased by 10-fold in comparison to normal or cancerous tissue. Determination of serum inhibin level may be used as a therapeutic tool to monitor prostate diseases.