Optical Resolution of Some Derivatives of D,L-Amino Acids by Chiral Liquid Chromatography
- 1 February 1986
- journal article
- research article
- Published by Taylor & Francis in Journal of Liquid Chromatography
- Vol. 9 (2-3) , 667-672
- https://doi.org/10.1080/01483918608076659
Abstract
Enantioselective interaction of silica-immobilized bovine serum albumin (BSA) with some amino acid derivatives has been investigated by chiral HPLC. High enantiomeric separation factors (α > 5) were found for N-(o-carboxybenzoyl)-alanine (Ia) and N-phthalimidothreonine (II). Both enantiomers of Ia were less retained than those of the precursor N-phtalimido-alanine (I). The N-benzenesulfonyl derivatives of serine and alanine were both optically resolved at low pH (5.8) with moderate α-values (1.3 and 1.5 respectively).This publication has 6 references indexed in Scilit:
- Direct liquid chromatographic separation of enantiomers on immobilized protein stationary phases : III. Optical resolution of a series of N-aroyl d,l-amino acids by high-performance liquid chromatography on bovine serum albumin covalently bound to silicaPublished by Elsevier ,2001
- Direct liquid chromatographic separation of enantiomers on immobilized protein stationary phases : IV. Molecular interaction forces and retention behaviour in chromatography on bovine serum albumin as a stationary phaseJournal of Chromatography A, 1984
- Separation of Enantiomers by Liquid Chromatographic MethodsPublished by Elsevier ,1983
- Direct resolution of enantiomers by liquid affinity chromatography on albumin-agarose under isocratic conditionsJournal of Chromatography A, 1982
- The Identification of the Amino Acids: p-Toluenesulfonyl1 Chloride as a ReagentJournal of the American Chemical Society, 1937
- Einige Condensationsproducte von Amidosäuren mit BenzolsulfonchloridEuropean Journal of Inorganic Chemistry, 1890