Duchenne Muscular Dystrophy Gene Expression in Normal and Diseased Human Muscle
- 18 March 1988
- journal article
- research article
- Published by American Association for the Advancement of Science (AAAS) in Science
- Vol. 239 (4846) , 1418-1420
- https://doi.org/10.1126/science.2450401
Abstract
A probe for the 5' end of the Duchenne muscular dystrophy (DMD) gene was used to study expression of the gene in normal human muscle, myogenic cell cultures, and muscle from patients with DMD. Expression was found in RNA from normal fetal muscle, adult cardiac and skeletal muscle, and cultured muscle after myoblast fusion. In DMD muscle, expression of this portion of the gene was also revealed by in situ RNA hybridization, particularly in regenerating muscle fibers.This publication has 16 references indexed in Scilit:
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