Thromboxane B2 Production During Erection

Abstract
The effect of erection on 6-keto-PGF1 .alpha. and thromboxane B2 in penile blood during electrically evoked erection was studied in the chacma baboon. 6-keto-PGF1 .alpha. remained at a low concentration, but thromboxane B2 showed a statistically significant rise 8-10 minutes after commencement of erection. Elevated thromboxane B2 during erection may potentiate platlet aggregation and may be one of the key events in the pathogenesis of ageing impotence.