Preliminary Evaluation of a Sensory and Psychomotor Functional Test Battery for Carpal Tunnel Syndrome: Part 1—Confirmed Cases and Normal Subjects

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Abstract
Two new computer-controlled functional tests were developed, known as the Wisconsin test battery, for carpal tunnel syndrome CTS). The gap detection sensory test quantifies tactile thresholds for areas of the hand innervated by the median nerve. The rapid pinch and release psychomotor test measures the initiation and control of specific muscles innervated by the median nerve motor branch. Ten confirmed CTS patients (based on electrophysiological parameters and examination; 18 CTS hands) and eight confirmed normal subjects (16 hands) with a similar average age were administered both tests. The CTS patients showed significant functional deficits for both tactility and psychomotor tests. Average CTS performance was 24 to 104% poorer than for the normal subjects, depending on the performance measure. The results indicated high correlations (r = 0.5 to 0.8) between median nerve electrophysiological parameters and tactility or psychomotor performance variables. No single functional test variable had sufficient sensitivity for detecting CTS among the subject pool. The combination of the two tests using 95% confidence level cutoff points achieved a sensitivity of 0.78 and a specificity of 0.81. Stepwise discriminant analysis resulted in two performance variables capable of a sensitivity of 0.72 and a specificity of 0.94 for differentiating well-defined CTS subjects from normal subjects. Despite these promising results, limitations of the study include small sample size and subject selection bias. Further studies are needed for verifying the utility of the functional test battery for detecting CTS in a general population.