The occurrence of skin cancer resulting from therapeutic and occupational irradiation with x-rays has been extensively documented clinically and amply confirmed experimentally since 1902, seven years after Roentgen's discovery.1,2It has been reported anywhere from 2 to more than 30 years after ionizing radiation,3and according to Willis the malignancy is "always of the squamous-cell type."4However, basalcell carcinomas have also been described,5and the case herein reported suggests that sebaceous carcinoma may also be included in the list of radiation-induced malignancies. This apparently is the first reported case illustrating the possibility that sebaceous carcinoma can arise as the result of radiation injury. Report of Case A 30-year-old white oil-delivery man was admitted to the Boston Veterans' Administration Hospital on Jan. 22, 1957, because of x-ray dermatitis of the face, neck, and upper chest. While in the Navy