Benzodiazepines—An Extensive Collection of Mass Spectra

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Abstract
An extensive collection of North American benzodiazepines including difficulty obtainable European and South American benzodiazepines (33 in total) were subjected to mass spectral examination to obtain electron impact ionization (El), positive methane chemical ionization (PCI) and negative chemical ionization (NCI) spectra. Most substances were amenable to gas chromatographic (GC) introduction to the mass spectrometer (MS), but where thermal degradation was encountered with GC-MS analysis, mass spectra of the particular benzodiazepines were recorded using the direct exposure probe (DEP) technique. Useful MS data for some end products and artifacts of degradation are included also. GC retention times are reported on both a retention indices basis as well as relative to proadifen internal standard. Disclosure of the sources of specimens, provision of their generic and trade names and respective structures, Chemical Abstracts numbers and names, render this compilation of benzodiazepines GC and MS data invaluable to the forensic toxicologist.