Response of F344 rats to inhalation of subclinical levels of sarin: exploring potential causes of Gulf War illness
- 1 June 2001
- journal article
- research article
- Published by SAGE Publications in Toxicology and Industrial Health
- Vol. 17 (5-10) , 294-297
- https://doi.org/10.1191/0748233701th105oa
Abstract
Subclinical, repeated exposures of F344 rats to sarin resulted in brain alterations in densities of chlonergic receptor subtypes that may be associated with memory loss and cognitive dysfunction. The exposures also depressed the immune system. The rat appears to be a good model for studying the effects of subclinical exposure to a nerve gas.Keywords
This publication has 3 references indexed in Scilit:
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- Subclinical Doses of the Nerve Gas Sarin Impair T Cell Responses through the Autonomic Nervous SystemToxicology and Applied Pharmacology, 2002
- Response of Rats to Low Levels of SarinToxicology and Applied Pharmacology, 2002