EFFECT OF PURIFIED PITUITARY PREPARATIONS ON THE INSULIN CONTENT OF THE RAT'S PANCREAS

Abstract
The effect of various hormones of the ant. pituitary on the insulin content of rat pancreas was investigated. Pure lactogenic hormone increased the insulin, growth hormone decreased it. The insulin-increasing action of crude adreno-corticotrophic preparations was attributed to contamination with lactogenic hormone. Lactogenic hormone showed pancreatrophic activity in both normal and hypophysectomized rats, while the opposite action of the growth hormone could be demonstrated in normal and adrenalectomized but not in hypophysectomized rats.

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