Effects of Field Size on the Survival of Pig Epidermal Colony-formingin Situafter Electron Irradiation
- 1 January 1995
- journal article
- research article
- Published by Taylor & Francis in International Journal of Radiation Biology
- Vol. 67 (1) , 79-83
- https://doi.org/10.1080/09553009514550101
Abstract
The survival of colony-forming cells in pig epidermis after irradiation was measured using different electron field sizes. The sensitivity of the colony-forming cells was characterized by D0 = 2·5–3·0 Gy. There was an effect of field size, described approximately by: Dose (to give five colonies/cm2) (Gy) = (31 ± 2) × Area−(0·048 ± 0·015). The effect of field size was less than found previously using tolerance to skin reactions (area exponent = 0·16). This work indicates for the first time that the effects of different large field sizes in skin can be detected at the level of colony-forming cell survival.Keywords
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