Selective in vitro inhibition of human molt-4 T lymphoblasts by the novel purine nucleoside phosphorylase inhibitor, CI-972
- 15 August 1991
- journal article
- Published by Elsevier in Biochemical and Biophysical Research Communications
- Vol. 178 (3) , 1351-1358
- https://doi.org/10.1016/0006-291x(91)91042-b
Abstract
No abstract availableKeywords
This publication has 12 references indexed in Scilit:
- Aspects of the purine nucleoside phosphorylase (PNP) deficient state produced in normal rats following oral administration of 8-amino-9-(2-thienylmethyl)guanine (PD 119,229), a novel inhibitor of PNPInflammation Research, 1987
- Preliminary report on 8-amino-9-(2-thienylmethyl)guanine (PD 119,229), a novel and potent purine nucleoside phosphorylase inhibitorInflammation Research, 1987
- 8-amino-9-substituted guanines: Potent purine nucleoside phosphorylase (PNP) inhibitorsInflammation Research, 1987
- Hyperuricemia: A Marker for Cell Energy CrisisNew England Journal of Medicine, 1987
- Inhibition of human purine nucleoside phosphorylase by acyclic nucleosides and nucleotidesBiochemical Pharmacology, 1987
- PROLONGATION OF SKIN GRAFT SURVIVAL IN DOGS TREATED WITH 8-AMINOGUANOSINETransplantation, 1986
- 2'-deoxyguanosine toxicity for B and mature T lymphoid cell lines is mediated by guanine ribonucleotide accumulation.Journal of Clinical Investigation, 1984
- Metabolism of deoxynucleosides by lymphocytes in long-term culture deficient in different purine enzymesBiochemical Pharmacology, 1984
- The metabolism of deoxyguanosine and guanosine in human B and T lymphoblasts. A role for deoxyguanosine kinase activity in the selective T-cell defect associated with purine nucleoside phosphorylase deficiencyBiochemical Journal, 1983
- Inhibitors of purine nucleoside phosphorylaseBiochemical Pharmacology, 1982