INTRA-UTERINE TRANSMISSION OF ANTHRAX
- 16 June 1923
- journal article
- research article
- Published by American Medical Association (AMA) in JAMA
- Vol. 80 (24) , 1769-1771
- https://doi.org/10.1001/jama.1923.02640510025011
Abstract
The possibility of the transmission of anthrax to the fetus of pregnant animals following the inoculation of these animals with anthrax cultures was denied for many years. Pollender, Brauell, Davaine, Bollinger, Wolff and others contended, as a result of experimental work, that the placenta of the experimental animals used afforded an impermeable barrier against this micro-organism. To Strauss and Chamberland1must be given the credit for proving that intra-uterine infection may be induced experimentally in animals. These investigators, by the use of modern methods (cultures and animal inoculation of these cultures), were able to prove that the placental barrier was not as impermeable as previous workers believed, and that while not constantly, yet in a good proportion of experiments, infection of the fetus could be produced. Subsequently, other writers confirmed these conclusions, using various animals (guinea-pigs, dogs, pigs) for inoculation. There are extremely few reports in the literature ofKeywords
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