EFFECT OF SYSTEMIC INFECTION AND RAISED SERUM IG-G CONCENTRATION ON D-XYLOSE TEST

  • 1 January 1977
    • journal article
    • research article
    • Vol. 67  (6) , 570-573
Abstract
Urinary D-xylose excretion was determined in 47 Zambian African patients during the 5 h after a 25 g oral load; some had systemic infections. Serum albumin, total globulin and .alpha.-globulin concentrations were determined in all the patients and immunoglobulin [Ig] (IgG, IgA, IgM and IgD) in 36 of them. An inverse association between the weight of xylose excreted and serum .alpha.-globulin (P < 0.02) and IgG (P < 0.002) concentrations was significant. There apparently was reduced xylose absorption in the presence of systemic infection. The mechanism of the association is unknown but seems to have a nutritional importance; systemic infections must be eradicated if the nutritional status of rural Africans is to be improved.

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