Teichoic acids in pathogenic Staphylococcus aureus

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Abstract
Strains (26) of S. aureus obtained from patients with endocarditis were studied for the production of .alpha.- and/or .beta.-ribitol teichoic acid (TA), using highly specific anti-TA antibodies prepared in rabbits. A counterimmunoelectrophoretic assay was used. .beta.-TA was the predominant residue produced by all strains; .alpha.-TA was found in all strains, but in smaller amounts and with much strain-to-strain variation. Antibodies in patients'' sera were found against .beta.-TA in higher titers and for longer periods than were anti-.beta.-TA antibodies. Antibodies against 1 or both TA residues were present in all but 1 of 26 patients.

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