Decrease in neutrophils observed in vivo in psoriatics after PUVA therapy
- 1 January 1978
- journal article
- research article
- Published by Springer Nature in Archives of Dermatological Research
- Vol. 262 (1) , 131-134
- https://doi.org/10.1007/bf00455580
Abstract
In 56 patients leucocyte and differential counts were done before and at weekly intervals during PUVA treatment of chronic recalcitrant psoriasis. A statistical significant (PP=0.02). The effect of PUVA therapy in psoriasis may be due to a decrease in the number of immunocompetent neutrophils demonstrated in psoriatic lesions. 56 Patienten mit chronischer behandlungsresistenter Psoriasis wurden mit PUVA behandelt. Unmittelbar vor Behandlungsanfang und danach einmal wöchentlich wurde eine qualitative und quantitative Bestimmung des weißen Blutbildes vorgenommen. Die Konzentration neutrophiler Granulocyten fiel während der ersten Behandlungswoche signifikant (PP=0,02). Der Effekt der PUVA Behandlung beruht möglicherweise auf einer Reduktion der Anzahl immunokompetenter neutrophiler Granulocyten in den Psoriasis-Plaques.This publication has 14 references indexed in Scilit:
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