T-cell subsets analyzed by monoclonal antibodies in patients with primary immunodeficiency diseases.

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Abstract
MINEGISHI, M., TSUCHIYA, S., IMAIZUMI, M., YAMAGUCHI, Y., KONNO, T. and TADA, K. T-Cell Subsets Analyzed by Monoclonal Antibodies in Patients with Primary Immunodeficiency Diseases. Tohoku J. exp. Med., 1984, 142 (3), 231-238 - The proportion of T-cell subsets was normal in all patients with X-linked agammaglobulinemia except for an 8-month patient who showed a decrease in OKT8+ T-cell population. In two patients with hypogammaglobulinemia with IgM production, T-cell subsets were normal in distribution and the patients' B cells produced only IgM in culture with autologous T cells. A patient with common variable immunodeficiency showed no imbalance in distribution of T-cell subsets. Imbalance of regulatory T-cell subsets was found in a patient with DiGeorge syndrome and severe combined immunodeficiency.