GEOGRAPHICAL DISTRIBUTION OF Hbbp ALLELE IN THE JAPANESE WILD MOUSE, MUS MUSCULUS MOLOSSINUS

Abstract
Electrophoretic survey of Hbb [.beta.-chain of Hb] alleles in the Japanese wild mouse, M. musculus molossinus, revealed a high incidence of Hbbp, the overall frequency of which in Japan was 56.6%. The Hbbd allele was also common (42.7%) but Hbb8 was rare (0.7%). Geographically, Hbbp allele is prevalent in the central regions of Japan, while Hbbd allele is more common in the peripheral regions. One possible explanation of this geographical distribution is the plural migration of wild mouse into Japan through either 2 southern routes and 1 northern route. On the global distribution profile of the 3 alleles, the house mouse seems to separate into 2 groups, Asian group and Western group, and M. musculus molossinus belongs to Asian group.