MANAGEMENT OF MERKEL CELL TUMOUR
- 1 December 1988
- journal article
- research article
- Published by Wiley in Anz Journal of Surgery
- Vol. 58 (12) , 971-974
- https://doi.org/10.1111/j.1445-2197.1988.tb00103.x
Abstract
The records of 13 patients suffering from Merkel cell tumour of the skin have been reviewed and the treatment analysed. Pending further experience of this uncommon tumour, a recommendation is made for wide excision of the primary site with elective postoperative radiation to both the primary site, the in-transit zone where practicable, and regional nodes. If malignant nodes occur, block dissection with postoperative radiotherapy is indicated. If widespread metastases develop, cyclophosphamide, doxorubicin, vincristine and prednisone chemotherapy may give a response. The prognosis is poor.Keywords
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