Inhibition of the aspartic proteinase from HIV‐2
- 14 August 1989
- journal article
- Published by Wiley in FEBS Letters
- Vol. 253 (1-2) , 214-216
- https://doi.org/10.1016/0014-5793(89)80961-5
Abstract
Kinetic constants were determined for the interaction of the HIV-2 aspartic proteinase with a synthetic substrate and a number of inhibitors at several pH values. Acetyl-pepstatin was more effective towards HIV-2 proteinase than the renin inhibitor, H-261; this effect is exactly the opposite from that observed previously for the proteinase from the HIV-1 AIDS virusKeywords
This publication has 5 references indexed in Scilit:
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