Abstract
Certain norcarotenoids, which have recently been found as excretion products of freshwater cyanobacteria and algae, are potent inhibitors of different metabolic functions in heterotrophic bacteria. 6-Methylhept-5-en-2-one showed the strongest effects and acted as a noncompetitive inhibitor of both glucose uptake and respiration by aquatic isolates of Chromobacterium lividum and Arthrobacter sp. Inhibition of the heterotrophic potential of glucose uptake by 6-methylhept-5-en-2-one was characterized by considerably lower inhibitor constants for bacterial cultures (Ki = 0.4 and 1.6 μM) than for a river water sample (Ki = 186.0 μM).

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