I-N: a newly described H-2 I subregion between K and I-A.

Open Access

1 February 1980

journal article
Published by Rockefeller University Press in The Journal of Experimental Medicine

Vol. 151 (2) , 481-485
https://doi.org/10.1084/jem.151.2.481

Abstract

Strong, primary mixed leukocyte culture-proliferative responses in certain K region-incompatible strain combinations led us to consider whether an I region-like locus might exist between K and I-A. Results obtained with an (A. TL X B10.D2)F1 anti-B10.BR serum provided serological evidence for a new locus; B10.T(6R)-absorbed serum retained reactivity on AQR lymphocytes. This finding demonstrates an antigen, Ia.W41, encoded by a locus, Ia-7, within a new I subregion, I-N.

Keywords

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