Depletion interactions in colloid-polymer mixtures

We present a neutron-scattering study of depletion interactions in a mixture of a hard-sphere-like colloid and a nonadsorbing polymer. By matching the scattering length density of the solvent with that of the polymer, we measured the partial structure factor $S_c\mathrm{}\left(Q\right)\mathrm{}$ for the colloidal particles. It is found that the measured $S_c\mathrm{}\left(Q\right)\mathrm{}$ for different colloid and polymer concentrations can be well described by an effective interaction potential $U\left(r\right)\mathrm{}$ for the polymer-induced depletion attraction between the colloidal particles. The magnitude of the attraction is found to increase linearly with the polymer concentration, but it levels off at higher polymer concentrations. This reduction in the depletion attraction presumably arises from the polymer-polymer interactions. The experiment demonstrates the effectiveness of using a nonadsorbing polymer to control the magnitude as well as the range of the interaction between the colloidal particles.