Quantification of human bocavirus in lower respiratory tract infections in China
Open Access
- 31 January 2007
- journal article
- Published by Springer Nature in Infectious Agents and Cancer
- Vol. 2 (1) , 3
- https://doi.org/10.1186/1750-9378-2-3
Abstract
A quantitative PCR method was established to quantify human bocavirus (HBoV) genomic copies in clinical specimens from children with lower respiratory tract infections (LRTI) in China. A total of 257 respiratory tract specimens were tested, and 7 (2.7%) of these (all sputum samples) were positive, with genomic copies that ranged from 8.0 × 103 to 8.0 × 109 in the samples. The main clinical symptom of patients who were positive for HBoV DNA was a pneumonia-like syndrome represented by high fever and cough. Our results suggest that HBoV may be an important etiological agent of LRTI in children in China.Keywords
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