On the geographical distribution of pseudocholinesterase variants

Abstract
Summary The incidence of pseudocholinesterase (PCHE=E.C. 3.1.1.8) variants in samples of 8 different populations (total of 2218 individuals) is reported. Together with proviously mentioned data from the literature, a general survey on the geographical distribution of PCHE isoenzymes is given. Possible reasons for present-day heterogenity of their distribution are also discussed. Concerning the incidence of the C5 variant, it is pointed out that the validity of applying population genetic models depends upon the accuracy of the genetic basis.