Abstract
For the patient with diffuse lung disease, lung biopsy has been a formidable procedure, and the clinician caring for such a patient has had to weigh most carefully the advantages of a tissue diagnosis against the potential risks of the biopsy procedure. Numerous technics for lung biopsy have been developed, and present a confusing array to the clinician faced with the management of a patient with a pulmonary lesion that requires a tissue diagnosis. Open-lung biopsy serves as the standard for diagnostic yield but causes a definite patient morbidity related to general anesthesia, postoperative pain and chest tubes. In addition, . . .