Familial acute myelogenous leukemia with associated c-monosomy in two affected members
- 1 August 1976
- Vol. 38 (2) , 841-845
- https://doi.org/10.1002/1097-0142(197608)38:2<841::aid-cncr2820380230>3.0.co;2-x
Abstract
A family is described in which five members, three sibs in one branch and two sib cousins in another, died of acute myelogenous leukemia. C‐Monosomy was found in the marrow of two of the sibs. C‐deletion aneuploidy has been increasingly reported in conjunction with abnormal myelopoiesis. It is possible that this chromosomal aberration may serve as a useful clinical marker of the emergence of a leukemic state.This publication has 19 references indexed in Scilit:
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