Studies on Oxyuriasis: XIV. Controlled Tests with Various Methods of Therapy

Publisher Website
Google Scholar
Abstract
Expts. were conducted in an effort to find a satisfactory treatment for pin-worm (Enterobius vermicularis) infection. Diagnoses were made by the NIH cellophane swab and the efficacy of the treatment was detd. by the use of 7 consecutive daily swabs at varying intervals after the termination of the treatment. When administered in a single dose daily over a period of 10 days, santonin was found less than 50% effective. Enemas consisting of a 12000 soln. of hexylresorcinol in water were of value in eradicating pinworm infections. The use of at least 10 such enemas spaced over a period of 3 weeks is necessary in most cases to eliminate the worms, although some cases require more prolonged treatment. Hexylresorcinol (Caprokol) in single doses orally failed to clear up infections. When the drug was given orally and by enema and repeated weekly for a period of 3 weeks, results were not promising. The use of hexylresorcinol (Caprokol) in a dilution of 1:1000 in a water-soluble jelly base inserted into the rectum at bedtime over varying periods of time was found ineffective in controlling pinworm infections. Some anal ointments are of value in allaying the pruritis caused by the migration of the $ worms but ointments in general are of little or no aid in control. Non-medicated enemas, such as soapsuds and saline enemas, are sometimes of value in the treatment of infants and young children, provided that the use of such enemas is continued for a sufficient period of time.

This publication has 0 references indexed in Scilit: