Histiocytosis X

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Abstract
A patient with histiocytosis X had nonhealing mouth lesions. Evaluation revealed diabetes insipidus and numerous bony lesions. EM of mouth lesions and lymph nodes did not indicate Langerhans cells, which were frequently described as occurring in histiocytosis X. A survey of 59 patients examined during 20 yr reported the presence of oral lesions in 42% of cases and confirmed the occurrence of a wide range of clinical patterns and variations in the course of the disease.

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