When and How to Treat Chronic Lymphocytic Leukemia

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Abstract
Chronic lymphocytic leukemia (CLL), the most common form of leukemia in adults, is usually recognized first by the patient's primary care physician. When the patient has other medical problems — which is frequently the case, given that the median age at diagnosis is 64 years — the primary care physician collaborates with the hematologist or oncologist in treating the patient. It is often difficult to make decisions about therapy, which can involve subtle factors that are best understood by the patient's own doctor.CLL most commonly arises from a malignant clone of B cells with a characteristic phenotype. It is . . .