FACTORS AFFECTING EVOLUTION OF FACTOR-XIA DURING BLOOD-COAGULATION

  • 1 January 1975
    • journal article
    • research article
    • Vol. 85  (5) , 826-831
Abstract
Earlier data indicated that Ca2+ was not required for the conversion of bovine or human factor XI to its activated form, but very little XIa was isolated from citrated or EDTA plasma, whether or not the plasma had been clotted by recalcification. Factor XIa activity was identified in resin-decalcified plasma, again with or without recalcification. Ca2+ apparently is not required for the evolution of factor XIa. There is probably no obligatory participation of cellular elements in the evolution of factor XIa during blood coagulation.