Anticancer Activity of Purine Antagonists and Their Ribosides. I. Comparative Studies with 6-Mercaptopurine and 6-Mercaptopurine Riboside.
- 1 May 1957
- journal article
- research article
- Published by Frontiers Media SA in Experimental Biology and Medicine
- Vol. 95 (1) , 135-138
- https://doi.org/10.3181/00379727-95-23144
Abstract
6-Mercaptopurine riboside was assayed for inhibitory activity against adenocarcinoma 755 in mice and was found to be of approximately the same activity as 6-mercaptopurine. Lines of S. faecalis resistant to 6-mercaptopurine were cross-resistant to 6-mercaptopurine riboside. A line of adenocarcinoma 755 selected for resistance to 6-mercaptopurine showed cross-resistance to 6-mercaptopurine riboside.Keywords
This publication has 2 references indexed in Scilit:
- Clinical Evaluation of a New Antimetabolite, 6-Mercaptopurine, in the Treatment of Leukemia and Allied DiseasesBlood, 1953
- STUDIES ON ANALOGS OF PURINES AND PYRIMIDINESAnnals of the New York Academy of Sciences, 1950