Malignant Hyperthermia in a Myopathic Child. Prolonged Postoperative Course Requiring Dantrolene

Abstract
An 18-mo.-old boy with congenital muscular dystrophy began to develop clear signs of the malignant hyperthermia syndrome after 85 min of halothane/N2O anesthesia. Dantrolene, 2 mg/kg i.v., was immediately effective, but temperature, heart rate and CO2 production were all increased for 2 days postoperatively in spite of repeated dantrolene administration.