ADENOCARCINOMA OF THE ENDOMETRIUM VAGINAL RECURRENCES AND MORTALITY

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Abstract
1. Patients with deep myometrial invasion are at risk for vaginal and/or pelvic recurrence. More intensive postoperative irradiation is indicated. 2. Patients with undifferentiated lesions are at high risk for vaginal and/or pelvic recurrence. These patients should have more intensive preoperative irradiation than we have previously given, to reduce the risk of local recurrence. 3. Both groups of patients are at risk for development of pelvic, abdominal and distant metastases. Early use of progestins when there is evidence of recurrent disease is recommended. Elective chemotherapy should be considered when a more effective agent is available than we presently have.

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