The TATA-Binding Protein: a General Transcription Factor in Eukaryotes and Archaebacteria
- 27 May 1994
- journal article
- other
- Published by American Association for the Advancement of Science (AAAS) in Science
- Vol. 264 (5163) , 1326-1329
- https://doi.org/10.1126/science.8191287
Abstract
The TATA-binding protein TBP appears to be essential for all transcription in eukaryotic cell nuclei, which suggests that its function was established early in evolution. Archaebacteria constitute a kingdom of organisms distinct from eukaryotes and eubacteria. Archaebacterial gene regulatory sequences often map to TATA box-like motifs. Here it is shown that the archaebacterium Pyrococcus woesei expresses a protein with structural and functional similarity to eukaryotic TBP molecules. This suggests that TBP's role in transcription was established before the archaebacterial and eukaryotic lineages diverged and that the transcription systems of archaebacteria and eukaryotes are fundamentally homologous.Keywords
This publication has 33 references indexed in Scilit:
- Crystal structure of a yeast TBP/TATA-box complexNature, 1993
- Functional dissection of TFIIB domains required for TFIIB–TFIID–promoter complex formation and basal transcription activityNature, 1993
- Mechanism of TATA-binding protein recruitment to a TATA-less class III promoterCell, 1992
- A suppressor of TBP mutations encodes an RNA polymerase III transcription factor with homology to TFIIBCell, 1992
- PCF4 encodes an RNA polymerase III transcription factor with homology to TFIIBCell, 1992
- TFIIB, an evolutionary link between the transcription machineries of archaebacteria and eukaryotesCell, 1992
- A yeast TFIIB-related factor involved in RNA polymerase III transcription.Genes & Development, 1992
- Dr1, a TATA-binding protein-associated phosphoprotein and inhibitor of class II gene transcriptionCell, 1992
- The TATA-binding protein: a central role in transcription by RNA polymerases I, II and IIITrends in Genetics, 1992
- Control regions of an archaeal gene: A TATA box and an initiator element promote cell-free transcription of the tRNAVal gene of Methanococcus vannieliiJournal of Molecular Biology, 1991