METHAEMOGLOBINAEMIA FOLLOWING THE USE OF PRILOCAINE (“CITANEST”)

Open Access

1 November 1964

journal article
research article
Published by Elsevier in British Journal of Anaesthesia

Vol. 36 (11) , 737-739
https://doi.org/10.1093/bja/36.11.737

Abstract

A series of eighty-one consecutive cases is reported in which continuous lumbar epidural block was performed on women in labour, prilocaine (Citanest) being the agent used. Nine cases showed cyanosis, and in seven of these spectroscopic examination of the blood showed methaemoglobinaemia. The relationship of prilocaine to aniline derivatives, known to cause methaemoglobinaemia, is mentioned.

Keywords

METHEMOGLOBINEMIA
PRILOCAINE
LOCAL ANESTHETIC LUMBAR EPIDURAL BLOCK
CYANOSIS
ANALGESIA
EPIDURAL
LABOR

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