EXPERIMENTAL ESOPHAGEAL AND PHARYNGOCERVICAL FISTULA

1 August 1951

journal article
research article
Published by American Medical Association (AMA) in Archives of Surgery

Vol. 63 (2) , 229-233
https://doi.org/10.1001/archsurg.1951.01250040233012

Abstract

ESOPHAGEAL fistulas in the laboratory animal have been utilized for a variety of experimental purposes. Pavlov and Schumova-Simanovskaia¹ used dogs with cervical and gastric fistulas in their studies on the relationship of the vagus nerves to gastric secretion. Pavlov² states that neck infection in the dog is serious and often fatal. In 1929 Saint and Mann³ cited the appalling mortality associated with experimental surgery of the esophagus and called attention to the factors of poor blood supply and lack of a true serosa. Saint⁴ later stressed the risk of fatal infection of the pleura and the cellular tissues of the neck. Allen⁵ mentions the frequency of mediastinitis during the course of experimental surgery when the lumen of the esophagus is opened. After the clinical experiences of Sturgeon⁶ and Lahey⁷ with esophageal diverticulas, both Allen⁵ and Markowitz⁸ advocated the use of two

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