Hypophosphorylation of Aqueous Humor sCD44 and Primary Open-Angle Glaucoma
- 1 August 2005
- journal article
- Published by Association for Research in Vision and Ophthalmology (ARVO) in Investigative Opthalmology & Visual Science
- Vol. 46 (8) , 2829-3577
- https://doi.org/10.1167/iovs.04-1472
Abstract
Purpose. Functional N-methyl-D-aspartate (NMDA) receptors (NMDARs) in Müller glia may influence glutamate neurotransmission through feedback loops between glia and neurons. The physiologic properties of NMDARs derive from the subunit composition of the tetrameric receptor. We characterized glycine binding to the NMDAR coagonist site in Müller cell membranes and determined NMDAR subunit expression in chick Müller glia compared with retinal neurons to make predictions about the heteromeric assembly of NMDARs.Keywords
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