URINARY 6β-HYDROXYCORTISOL IN ADRENOCORTICAL HYPERFUNCTION*†
- 1 March 1961
- journal article
- research article
- Published by The Endocrine Society in Journal of Clinical Endocrinology & Metabolism
- Vol. 21 (3) , 263-270
- https://doi.org/10.1210/jcem-21-3-263
Abstract
Three patients with abnormal amounts of 6β-hydroxycortisol in the urine are presented. In 2 of these patients, adrenal hyperplasia was found at autopsy. The third patient had Cushing-like clinical symptoms, and an adrenal adenoma was found at operation; in this case, although the excretion of 6β-hydroxycortisol was elevated, the urinary alpha-ketolic steroid pattern was otherwise normal. Technics for the isolation of 6β-hydroxycortisol are described.Keywords
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