Mefenamic Acid Blood and Urine Levels in the Horse Determined by Derivative Gas-Liquid Chromatography -- Electron Capture
- 1 April 1976
- journal article
- research article
- Published by Oxford University Press (OUP) in Journal of Chromatographic Science
- Vol. 14 (4) , 201-203
- https://doi.org/10.1093/chromsci/14.4.201
Abstract
Mefenamic acid is extracted from biological fluids and is acylated with pentafluoropropionic anhydride to form a derivative possessing high electron affinity. This derivative is analyzed by gas-liquid chromatography with an electron capture detector. The method is particularly valuable for determining drug levels in blood where small sample and/or drug concentrations are available.Keywords
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