Choice Behavior of Drosophila Facing Contradictory Visual Cues
- 16 November 2001
- journal article
- other
- Published by American Association for the Advancement of Science (AAAS) in Science
- Vol. 294 (5546) , 1543-1547
- https://doi.org/10.1126/science.1058237
Abstract
We studied the underlying neural mechanism of a simple choice behavior between competing alternatives in Drosophila . In a flight simulator, individual flies were conditioned to choose one of two flight paths in response to color and shape cues; after the training, they were tested with contradictory cues. Wild-type flies made a discrete choice that switched from one alternative to the other as the relative salience of color and shape cues gradually changed, but this ability was greatly diminished in mutant ( mbm 1 ) flies with miniature mushroom bodies or with hydroxyurea ablation of mushroom bodies. Thus, Drosophila genetics may be useful for elucidating the neural basis of choice behavior.Keywords
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