Ca2+-induced polyphosphoinositide breakdown due to phosphomonoesterase activity in chicken erythrocytes
- 1 October 1985
- journal article
- research article
- Published by Portland Press Ltd. in Biochemical Journal
- Vol. 231 (1) , 179-183
- https://doi.org/10.1042/bj2310179
Abstract
Treatment of chicken erythrocytes with ionophore A23187 and Ca2+ caused the breakdown of a large proportion of the cellular polyphosphoinositides. Since no diacylglycerol or phosphatidate was generated, but there was a small increase in the level of phosphatidylinositol, it was concluded that breakdown occurred as a result of phosphomonoesterase activation. Experiments with subcellular fractions showed that the phosphomonoesterase activity was present in the cytosolic fraction of the cells.This publication has 23 references indexed in Scilit:
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