PROGNOSTIC FACTORS PREDICTING THE OUTCOME OF SARCOIDOSIS - AN ANALYSIS OF 818 PATIENTS

  • 1 January 1983
    • journal article
    • research article
    • Vol. 52  (208) , 525-533
Abstract
A computerized, retrospective study of 818 patients with sarcoidosis was analyzed to study the prognosis of each individual manifestation of the disease. The good prognosis of erythema nodosum, acute arthritis and bilateral hilar lymphadenopathy was confirmed, though 16% of patients presenting with erythema nodosum pursued a chronic course. Cor pulmonale and nephrocalcinosis reflected the poorest prognosis, while lupus pernio and sarcoidosis of the mucosa of the upper respiratory tract rarely resolved. Bone sarcoidosis also implied chronicity, but in 4 of 31 patients there was no clinical evidence of disease activity 2 yr after the initial diagnosis, although naturally the bone radiograph was still abnormal. Hepatomegaly carried a worse prognosis than splenomegaly, or indeed, than the finding of pulmonary mottling without hilar glands, a stage 3 chest radiograph.

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