Effect of hormones on ceruloplasmin and copper concentrations in the plasma of the rat
- 30 April 1968
- journal article
- research article
- Published by American Physiological Society in American Journal of Physiology-Legacy Content
- Vol. 214 (5) , 1152-1154
- https://doi.org/10.1152/ajplegacy.1968.214.5.1152
Abstract
Ceruloplasmin and plasma copper concentrations in the albino rat continually increase from bith, reaching a peak between 9 and 12 months of age. In the adrenalectomized rat, ceruloplasmin and plasma Cu were significantly higher than normal up to 10 months after surgery. Subcutaneous gelatin injections caused a significant ceruloplasmin and plasma Cu increase. ACTH in gelatin inhibited the ceruloplasmin and plasma Cu increase accompanying gelatin injections. Sodium levothyroxine injections significantly decreased the ceruloplasmin and plasma Cu of both the neonatal and adult rat. Cortisone acetate and sodium levothyroxine injected at birth caused a significant increase in ceruloplasmin and plasma Cu in the mature rat.This publication has 1 reference indexed in Scilit:
- Blood copper variation among speciesAmerican Journal of Physiology-Legacy Content, 1967