A CASE OF PSEUDOHYPOPARATHYROIDISM PRESENTING AS EPILEPSY WITH INCREASED PARATHYROID HORMONE-LIKE ACTIVITY IN URINE

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Abstract
A case of pseudohypoparathyroidism was reported. The patient, a 13 years old male, complained of headache, convulsive seizures, and short spells of unconsciousness for the last 2 months. Typical clinical features for pseudohypoparathyroidism such as short stature, round face, subcutaneous calcification, lack of phosphaturic response to parathyroid extract, hypocalcemia, and hyperphosphatemia were noted.. Benzonic acid extract of the urine revealed an increased parathyroid hormone-like Ca-mobilizing activity, which decreased after treatment with AT-10 [dihydrotachysterol], and a normal phosphaturic activity. Parathyroid hyperfunction due to the target organ failure may be suggested although no other evidence of secondary hyperparathyroidism was demonstrated.

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