Granulocyte Kinetics after Thermal Injury

Abstract
A 30% third-degree burn in rats was used to study granulocyte kinetics after thermal injury. Early postburn leukocytosis, a result of granulocyte demargination and early bone marrow release, was followed by an absolute granulocytopenia, despite elevated concentrations of circulating cells. The total peripheral granulocyte pool was slowly restored to normal in the presence of increased marrow production and release and the re-establishment of a marginating pool.

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