STIMULATION OF CELL-MEDIATED RESISTANCE IN MICE TO INFECTION WITH LISTERIA-MONOCYTOGENES BY VITAMIN-A

  • 1 January 1979
    • journal article
    • research article
    • Vol. C130  (4) , 587-594
Abstract
Vitamin A given as retinol acetate, retinol palmitate and the derivatives retinoic acid and a retinoid strongly fortified the resistance of mice to infection with virulent L. monocytogene cells. Strong resistance enhancement was only achieved when high toxic vitamin A doses were given. This effect was due to stimulation of function of the mononuclear phagocytic system rather than of the T [thymus-derived] lymphocyte.

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