Molecular mimicry: a critical look at exemplary instances in human diseases
- 1 April 2000
- journal article
- review article
- Published by Springer Nature in Cellular and Molecular Life Sciences
- Vol. 57 (4) , 542-551
- https://doi.org/10.1007/pl00000716
Abstract
Molecular mimicry, the concept that antigenic determinants of microorganisms resemble antigenic determinants of the host, is frequently cited as a plausible mechanism to account for the association of infection and autoimmune disease. Based on analogous sequences of amino acids or on cross-reactions of monoclonal antibodies, numerous examples of such mimicry have been reported. There are, however, no clear examples of a human disease caused by molecular mimicry.Keywords
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